Fabrication of a drug delivery system that enhances antifungal drug corneal penetration

Fabrication of a drug delivery system that enhances antifungal drug corneal penetration

Fungal keratitis (FK) remains a severe eye disease, and effective therapies are limited by drug shortages and critical ocular barriers. Despite the high antifungal potency and broad spectrum of econazole, its strong irritant and insolubility in water hinder its ocular application. We designed and fa...

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Bibliographic Details
Main Authors: Jingguo Li, Zhanrong Li, Zhen Liang, Lei Han, Huayang Feng, Siyu He, Junjie Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
fungal keratitis
corneal penetration
polymeric vector
pharmacokinetics
dual fluorescent label
Online Access:http://dx.doi.org/10.1080/10717544.2018.1461278

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