Summary: | Two young patients with cholangiocarcinoma associated with
salmonella carriage and ulcerative colitis, respectively, were seen at a community-
based university hospital. This experience prompted a review of all cases
with this tumour seen in the past decade. Twenty-seven patients were found.
Their clinical, laboratory, and histological features, and therapeutic outcome are
described. Of the group, only 7.4% were younger than 30 years of age and 14.8%
had recognized associated conditions. The most common definable tumour was
a well differentiated hilar cholangiocarcinoma. Overall outcome was poor (six
months). Survival was similar in patients undergoing palliative stents or surgery.
In a small subgroup of surgically treated patients who received either radiotherapy
or postoperative drainage, survival seemed to be better.
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