Ferulic acid ameliorates nonalcoholic fatty liver disease and modulates the gut microbiota composition in high-fat diet fed ApoE−/− mice

Ferulic acid ameliorates nonalcoholic fatty liver disease and modulates the gut microbiota composition in high-fat diet fed ApoE−/− mice

The objective of this study was to investigate the effects of ferulic acid (FA) on nonalcoholic fatty liver disease (NAFLD) and gut microbiota, and its regulation mechanism in ApoE−/− mice fed on a high-fat diet (HFD). Liver morphology, blood lipids, gut microbiota and their metabolite indole-3-acet...

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Bibliographic Details
Main Authors: Yunci Ma, Kai Chen, Lin Lv, Shaoyu Wu, Zhijian Guo
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ferulic acid
Nonalcoholic fatty liver disease
AHR
FASN
SREBP-1c
Gut microbiota
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218387456

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http://www.sciencedirect.com/science/article/pii/S0753332218387456

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