Temporary Fertility Decline after Large Rubella Outbreak, Japan

Japan experienced 2 large rubella epidemics in 2004 and 2012–2014. Because of suboptimal immunization levels, the country has been experiencing a third major outbreak during 2018–2020. We conducted time series analyses to evaluate the effect of the 2012–2014 nationwide rubella epidemic on prefecture...

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Main Authors: Kenji Mizumoto, Gerardo Chowell
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2020-06-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/26/6/18-1718_article
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spelling doaj-e22388eb6c9d4faab85bab5599fe042c2020-11-25T02:19:04ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592020-06-012661122112910.3201/eid2606.181718Temporary Fertility Decline after Large Rubella Outbreak, JapanKenji MizumotoGerardo ChowellJapan experienced 2 large rubella epidemics in 2004 and 2012–2014. Because of suboptimal immunization levels, the country has been experiencing a third major outbreak during 2018–2020. We conducted time series analyses to evaluate the effect of the 2012–2014 nationwide rubella epidemic on prefecture-level natality in Japan. We identified a statistically significant decline in fertility rates associated with rubella epidemic activity and increased Google searches for the term “rubella.” We noted that the timing of fertility declines in 2014 occurred 9–13 months after peak rubella incidence months in 2013 in 4 prefectures with the highest rubella incidence. Public health interventions should focus on enhancing vaccination campaigns against rubella, not only to protect pregnant women from infection but also to mitigate declines in population size and birth rates.https://wwwnc.cdc.gov/eid/article/26/6/18-1718_articlerubellavaccine-preventable diseasesoutbreaktime seriesbirth riskviruses
collection DOAJ
language English
format Article
sources DOAJ
author Kenji Mizumoto
Gerardo Chowell
spellingShingle Kenji Mizumoto
Gerardo Chowell
Temporary Fertility Decline after Large Rubella Outbreak, Japan
Emerging Infectious Diseases
rubella
vaccine-preventable diseases
outbreak
time series
birth risk
viruses
author_facet Kenji Mizumoto
Gerardo Chowell
author_sort Kenji Mizumoto
title Temporary Fertility Decline after Large Rubella Outbreak, Japan
title_short Temporary Fertility Decline after Large Rubella Outbreak, Japan
title_full Temporary Fertility Decline after Large Rubella Outbreak, Japan
title_fullStr Temporary Fertility Decline after Large Rubella Outbreak, Japan
title_full_unstemmed Temporary Fertility Decline after Large Rubella Outbreak, Japan
title_sort temporary fertility decline after large rubella outbreak, japan
publisher Centers for Disease Control and Prevention
series Emerging Infectious Diseases
issn 1080-6040
1080-6059
publishDate 2020-06-01
description Japan experienced 2 large rubella epidemics in 2004 and 2012–2014. Because of suboptimal immunization levels, the country has been experiencing a third major outbreak during 2018–2020. We conducted time series analyses to evaluate the effect of the 2012–2014 nationwide rubella epidemic on prefecture-level natality in Japan. We identified a statistically significant decline in fertility rates associated with rubella epidemic activity and increased Google searches for the term “rubella.” We noted that the timing of fertility declines in 2014 occurred 9–13 months after peak rubella incidence months in 2013 in 4 prefectures with the highest rubella incidence. Public health interventions should focus on enhancing vaccination campaigns against rubella, not only to protect pregnant women from infection but also to mitigate declines in population size and birth rates.
topic rubella
vaccine-preventable diseases
outbreak
time series
birth risk
viruses
url https://wwwnc.cdc.gov/eid/article/26/6/18-1718_article
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