18F-C2Am: a targeted imaging agent for detecting tumor cell death in vivo using positron emission tomography

18F-C2Am: a targeted imaging agent for detecting tumor cell death in vivo using positron emission tomography

Abstract Introduction Trialing novel cancer therapies in the clinic would benefit from imaging agents that can detect early evidence of treatment response. The timing, extent and distribution of cell death in tumors following treatment can give an indication of outcome. We describe here an 18F-label...

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Bibliographic Details
Main Authors: Flaviu Bulat, Friederike Hesse, De-En Hu, Susana Ros, Connor Willminton-Holmes, Bangwen Xie, Bala Attili, Dmitry Soloviev, Franklin Aigbirhio, Finian. J. Leeper, Kevin M. Brindle, André A. Neves
Format: Article
Language:English
Published: SpringerOpen 2020-12-01
Series:EJNMMI Research
Subjects:
Cell death
PET
C2Am
Synaptotagmin-I
Tumor
TRAILR2
Online Access:https://doi.org/10.1186/s13550-020-00738-7

Internet

https://doi.org/10.1186/s13550-020-00738-7

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