Anticancer Activity Evaluation of New Thieno[2,3-d]pyrimidin-4(3H)-ones and Thieno[3,2-d]pyrimidin-4(3H)-one Derivatives

Anticancer Activity Evaluation of New Thieno[2,3-d]pyrimidin-4(3H)-ones and Thieno[3,2-d]pyrimidin-4(3H)-one Derivatives

Anticancer screening of several novel thienopyrimidines has been performed. The thienopyrimidine derivatives were synthesized from available starting materials according to the convenient synthetic procedures using a one-pot solvent-free reaction which gave a wide access to thienopyrimidine-derivati...

Full description

Bibliographic Details
Main Authors: Olga Shyyka, Nazariy Pokhodylo, Nataliya Finiuk, Vasyl Matiychuk, Rostyslav Stoika, Mykola Obushak
Format: Article
Language:English
Published: Österreichische Apotheker-Verlagsgesellschaft m. b. H. 2018-07-01
Series:Scientia Pharmaceutica
Subjects:
anticancer activity
2-R3,R4-amino-5-R1-6-R2-thieno[2,3-d]pyrimidin-4(3H)-ones
2-R3,R4-amino-5-R1-6-R2-thieno[3,2-d]pyrimidin-4(3H)-ones
molecular docking
Online Access:http://www.mdpi.com/2218-0532/86/3/28

Internet

http://www.mdpi.com/2218-0532/86/3/28

Similar Items