Phytoconstituents of Adenanthera pavonina Linn from the bark extracts

• Main Authors: Arzumand Ara, Md. Moshfekus Saleh-E-In, Md. Abul Hashem, Mesbahuddin Ahmad, Choudhury Mahmood Hasan
• Format: Article
• Language: English
• Published: SpringerOpen 2019-12-01
• Series: Beni-Suef University Journal of Basic and Applied Sciences
• Subjects: Adenanthera pavonina; Bark; Dichloromethane extract; Ethyl acetate extract; Chromatography
• Online Access: https://doi.org/10.1186/s43088-019-0013-0

Abstract Background Adenanthera pavonina L. is an important medicinal plant and its barks are used in traditional medicine for treating different diseases. Therefore, a phytochemical investigation was carried out to isolate and identify secondary metabolites from its barks. Results Seven compounds namely ethyl 3,3-dimethyl-13-hydroxytridecanoate (1), stigmasta-5,22-dien-3β-ol (2), tert.butyl tridecanoate (3), 6-α-hydroxy stigmast-20(21)-en-3-one (4) of dichloromethane extract and 18-(2′, 3′-dihydroxyphenyl)nonadec-17-en-2-ol (5), 1-(N-propyl amino)-2-henecosanone (6), and stigmast–5(6), 20(21)-diene-3-one (7) were isolated from the barks of Adenanthera pavonina Linn. Of these compounds, 1, 4, 5, 6, and 7 appear new. The structures of these compounds were elucidated by spectroscopic techniques, mainly by NMR. Conclusions Five new and two known compounds have been isolated and characterized from the bark of A. pavonina. The isolated compounds could be a potential template for the synthesis and development of new lead compounds with interesting pharmacological properties. Graphical abstract