Nicotinic acetylcholine receptor agonists attenuate septic acute kidney injury in mice by suppressing inflammation and proteasome activity.

Nicotinic acetylcholine receptor agonists attenuate septic acute kidney injury in mice by suppressing inflammation and proteasome activity.

Sepsis is one of the leading causes of acute kidney injury (AKI). Septic patients who develop acute kidney injury (AKI) are at increased risk of death. To date there is no effective treatment for AKI or septic AKI. Based on their anti-inflammatory properties, we examined the effects of nicotinic ace...

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Bibliographic Details
Main Authors: Prodyot K Chatterjee, Michael M Yeboah, Oonagh Dowling, Xiangying Xue, Saul R Powell, Yousef Al-Abed, Christine N Metz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3346807?pdf=render

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http://europepmc.org/articles/PMC3346807?pdf=render

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