Neuroprotective Effects of Curcumin on IL-1β-Induced Neuronal Apoptosis and Depression-Like Behaviors Caused by Chronic Stress in Rats

Neuroprotective Effects of Curcumin on IL-1β-Induced Neuronal Apoptosis and Depression-Like Behaviors Caused by Chronic Stress in Rats

Depression is suggested to be a neuropsychiatric disease resulting from neuroinflammation within specific brain regions. Curcumin, a potential neuroprotective agent extracted from curcuma loga, exerts antidepressant-like effects in various animal models of depression. However, the underlying mechani...

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Bibliographic Details
Main Authors: Cuiqin Fan, Qiqi Song, Peng Wang, Ye Li, Mu Yang, Shu Yan Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
interleukin-1β
apoptosis
inflammation
curcumin
depression
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00516/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00516/full

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