Exploring the conservation of Alzheimer-related pathways between H. sapiens and C. elegans: a network alignment approach

Abstract Alzheimer disease (AD) is a neurodegenerative disorder with an –as of yet– unclear etiology and pathogenesis. Research to unveil disease processes underlying AD often relies on the use of neurodegenerative disease model organisms, such as Caenorhabditis elegans. This study sought to identif...

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Bibliographic Details
Main Authors: Avgi E. Apostolakou, Xhuliana K. Sula, Katerina C. Nastou, Georgia I. Nasi, Vassiliki A. Iconomidou
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83892-9