Till 2018: a survey of biomolecular sequences in genus Panax

• Main Authors: Vinothini Boopathi, Sathiyamoorthy Subramaniyam, Ramya Mathiyalagan, Deok-Chun Yang
• Format: Article
• Language: English
• Published: Elsevier 2020-01-01
• Series: Journal of Ginseng Research
• Online Access: http://www.sciencedirect.com/science/article/pii/S1226845319300326

Ginseng is popularly known to be the king of ancient medicines and is used widely in most of the traditional medicinal compositions due to its various pharmaceutical properties. Numerous studies are being focused on this plant's curative effects to discover their potential health benefits in most human diseases, including cancer— the most life-threatening disease worldwide. Modern pharmacological research has focused mainly on ginsenosides, the major bioactive compounds of ginseng, because of their multiple therapeutic applications. Various issues on ginseng plant development, physiological processes, and agricultural issues have also been studied widely through state-of-the-art, high-throughput sequencing technologies. Since the beginning of the 21st century, the number of publications on ginseng has rapidly increased, with a recent count of more than 6,000 articles and reviews focusing notably on ginseng. Owing to the implementation of various technologies and continuous efforts, the ginseng plant genomes have been decoded effectively in recent years. Therefore, this review focuses mainly on the cellular biomolecular sequences in ginseng plants from the perspective of the central molecular dogma, with an emphasis on genomes, transcriptomes, and proteomes, together with a few other related studies. Keywords: EST, genome, next-generation sequencing, Panax species, transcriptome