Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex

Medial entorhinal cortex (MEC) is involved in memory processes that entail the replay of sequential firing of hippocampal place cells during rest periods and during behaviour. Here, the authors show that MEC lesioned animals show intact replay after an epoch of rats running on a linear track, while...

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Bibliographic Details
Main Authors: Alireza Chenani, Marta Sabariego, Magdalene I. Schlesiger, Jill K. Leutgeb, Stefan Leutgeb, Christian Leibold
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09280-0