Efficacy and safety of praziquantel in preschool-aged and school-aged children infected with Schistosoma mansoni: a randomised controlled, parallel-group, dose-ranging, phase 2 trial

Background: Praziquantel has been the drug of choice for schistosomiasis control for more than 40 years, yet surprisingly, the optimal dose for children younger than 4 years is not known. We aimed to assess the efficacy and safety of escalating praziquantel dosages in preschool-aged children (PSAC)....

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Bibliographic Details
Main Authors: Jean T Coulibaly, PhD, Gordana Panic, PhD, Kigbafori D Silué, PhD, Jana Kovač, MSc, Jan Hattendorf, PhD, Prof Jennifer Keiser, PhD
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:The Lancet Global Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2214109X17301870