Novel antibody against a glutamic acid-rich human fibrinogen-like protein 2-derived peptide near Ser91 inhibits hfgl2 prothrombinase activity.

Novel antibody against a glutamic acid-rich human fibrinogen-like protein 2-derived peptide near Ser91 inhibits hfgl2 prothrombinase activity.

Fibrinogen-like protein 2 (fgl2) is highly expressed in microvascular endothelial cells in diseases associated with microcirculatory disturbances and plays a crucial role in microthrombosis. Previous studies have demonstrated that the Ser89 residue is a critical site for mouse fgl2 prothrombinase ac...

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Bibliographic Details
Main Authors: Wen-Zhu Li, Jue Wang, Rui Long, Guan-Hua Su, Dinesh-Kumar Bukhory, Jing Dai, Nan Jin, Shi-Yuan Huang, Peng Jia, Ting Li, Chen Fan, Kun Liu, Zhaohui Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3984148?pdf=render

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