Asperlin Inhibits LPS-Evoked Foam Cell Formation and Prevents Atherosclerosis in ApoE−/− Mice

Asperlin Inhibits LPS-Evoked Foam Cell Formation and Prevents Atherosclerosis in ApoE−/− Mice

Asperlin is a marine-derived natural product with antifungal and anti-inflammatory activities in vitro. In the present study, we isolated asperlin from a marine Aspergillus versicolor LZD4403 fungus and investigated its anti-atherosclerotic effects in vitro and in vivo. Asperlin significantly inhibi...

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Bibliographic Details
Main Authors: Yue Zhou, Ran Chen, Dong Liu, Chongming Wu, Peng Guo, Wenhan Lin
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Marine Drugs
Subjects:
asperlin
inflammation
macrophage
M1/M2 polarization
atherosclerosis
foam cell
Online Access:https://www.mdpi.com/1660-3397/15/11/358

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