Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus

<p>Abstract</p> <p>Background</p> <p>Insulin dependent (i.e., "type 1") diabetes mellitus (T1DM) is considered to be a T cell mediated disease in which T<sub>H</sub>1 and T<sub>c </sub>autoreactive cells attack the pancreatic islets. Am...

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Bibliographic Details
Main Authors: Steinman Lawrence, DeVoss Jason, Tsai Mindy, Sanna Maija, Pedotti Rosetta, McDevitt Hugh, Galli Stephen J
Format: Article
Language:English
Published: BMC 2003-02-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/4/2