A 3D Fiber‐Hydrogel Based Non‐Viral Gene Delivery Platform Reveals that microRNAs Promote Axon Regeneration and Enhance Functional Recovery Following Spinal Cord Injury

A 3D Fiber‐Hydrogel Based Non‐Viral Gene Delivery Platform Reveals that microRNAs Promote Axon Regeneration and Enhance Functional Recovery Following Spinal Cord Injury

Abstract Current treatment approaches toward spinal cord injuries (SCI) have mainly focused on overcoming the inhibitory microenvironment that surrounds lesion sites. Unfortunately, the mere modulation of the cell/tissue microenvironment is often insufficient to achieve desired functional recovery....

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Bibliographic Details
Main Authors: Na Zhang, Junquan Lin, Vincent Po Hen Lin, Ulla Milbreta, Jiah Shin Chin, Elaine Guo Yan Chew, Michelle Mulan Lian, Jia Nee Foo, Kunyu Zhang, Wutian Wu, Sing Yian Chew
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Advanced Science
Subjects:
electrospinning
hydrogel
neural tissue engineering
RNA interference
RNA sequencing
Online Access:https://doi.org/10.1002/advs.202100805

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