Single-Cell RNA Sequencing Identifies New Inflammation-Promoting Cell Subsets in Asian Patients With Chronic Periodontitis

Single-Cell RNA Sequencing Identifies New Inflammation-Promoting Cell Subsets in Asian Patients With Chronic Periodontitis

Periodontitis is a highly prevalent chronic inflammatory disease leading to periodontal tissue breakdown and subsequent tooth loss, in which excessive host immune response accounts for most of the tissue damage and disease progression. Despite of the imperative need to develop host modulation therap...

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Bibliographic Details
Main Authors: Shu-jiao Qian, Qian-ru Huang, Rui-ying Chen, Jia-ji Mo, Lin-yi Zhou, Yi Zhao, Bin Li, Hong-chang Lai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
single-cell sequencing
gingiva
periodontitis
inflammatory microenvironment
mucosa
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.711337/full

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