HNF4A-AS1/hnRNPU/CTCF axis as a therapeutic target for aerobic glycolysis and neuroblastoma progression

HNF4A-AS1/hnRNPU/CTCF axis as a therapeutic target for aerobic glycolysis and neuroblastoma progression

Abstract Background Aerobic glycolysis is a hallmark of metabolic reprogramming that contributes to tumor progression. However, the mechanisms regulating expression of glycolytic genes in neuroblastoma (NB), the most common extracranial solid tumor in childhood, still remain elusive. Methods Crucial...

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Bibliographic Details
Main Authors: Huajie Song, Dan Li, Xiaojing Wang, Erhu Fang, Feng Yang, Anpei Hu, Jianqun Wang, Yanhua Guo, Yang Liu, Hongjun Li, Yajun Chen, Kai Huang, Liduan Zheng, Qiangsong Tong
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Hematology & Oncology
Subjects:
Hepatocyte nuclear factor 4 alpha antisense RNA 1
Heterogeneous nuclear ribonucleoprotein U
CCCTC-binding factor
Aerobic glycolysis
Tumor progression
Neuroblastoma
Online Access:http://link.springer.com/article/10.1186/s13045-020-00857-7

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http://link.springer.com/article/10.1186/s13045-020-00857-7

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