The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis

The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis

The results of 77 M. tuberculosis clinical isolates genetic typing, allocated from patients with extensive destructive infiltrative and disseminated pulmonary tuberculosis are presented in the article. It is established that among genetically non-uniform Mycobacterium tuberculosis strains, circulati...

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Main Authors: O. V. Voronkova, O. I. Urazova, R. R. Khasanova, V. V. Novitsky, Ye. G. Churina, I. O. Naslednikova, O. V. Filinyuk, V. A. Serebryakova, Yu. V. Kolobovnikova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2011-02-01
Series:Bûlleten' Sibirskoj Mediciny
Subjects:
mycobacterium tuberculosis
genetic typing
genetic profile
drag resistance
Online Access:https://bulletin.tomsk.ru/jour/article/view/1308
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spelling doaj-e19c41fb4fcd46e99dc319215ec501d92021-07-29T08:37:53ZengSiberian State Medical University (Tomsk)Bûlleten' Sibirskoj Mediciny1682-03631819-36842011-02-01101121710.20538/1682-0363-2011-1-12-17831The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosisO. V. Voronkova0O. I. Urazova1R. R. Khasanova2V. V. Novitsky3Ye. G. Churina4I. O. Naslednikova5O. V. Filinyuk6V. A. Serebryakova7Yu. V. Kolobovnikova8Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетThe results of 77 M. tuberculosis clinical isolates genetic typing, allocated from patients with extensive destructive infiltrative and disseminated pulmonary tuberculosis are presented in the article. It is established that among genetically non-uniform Mycobacterium tuberculosis strains, circulating in Tomsk and the Tomsk Region, and causing acute progressive destructive pulmonary tuberculosis, 19% show multi drag resistance. Beijing family strains make 27% from the general population, have a high clusterization index (74%), level of their multi drag resistance in 3 times exceeds that at «not Beijing» strains for which the share of clustering strains makes 11%.https://bulletin.tomsk.ru/jour/article/view/1308mycobacterium tuberculosisgenetic typinggenetic profiledrag resistance
collection DOAJ
language English
format Article
sources DOAJ
author O. V. Voronkova
O. I. Urazova
R. R. Khasanova
V. V. Novitsky
Ye. G. Churina
I. O. Naslednikova
O. V. Filinyuk
V. A. Serebryakova
Yu. V. Kolobovnikova
spellingShingle O. V. Voronkova
O. I. Urazova
R. R. Khasanova
V. V. Novitsky
Ye. G. Churina
I. O. Naslednikova
O. V. Filinyuk
V. A. Serebryakova
Yu. V. Kolobovnikova
The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
Bûlleten' Sibirskoj Mediciny
mycobacterium tuberculosis
genetic typing
genetic profile
drag resistance
author_facet O. V. Voronkova
O. I. Urazova
R. R. Khasanova
V. V. Novitsky
Ye. G. Churina
I. O. Naslednikova
O. V. Filinyuk
V. A. Serebryakova
Yu. V. Kolobovnikova
author_sort O. V. Voronkova
title The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
title_short The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
title_full The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
title_fullStr The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
title_full_unstemmed The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
title_sort genotypical characteristic of m. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
publisher Siberian State Medical University (Tomsk)
series Bûlleten' Sibirskoj Mediciny
issn 1682-0363
1819-3684
publishDate 2011-02-01
description The results of 77 M. tuberculosis clinical isolates genetic typing, allocated from patients with extensive destructive infiltrative and disseminated pulmonary tuberculosis are presented in the article. It is established that among genetically non-uniform Mycobacterium tuberculosis strains, circulating in Tomsk and the Tomsk Region, and causing acute progressive destructive pulmonary tuberculosis, 19% show multi drag resistance. Beijing family strains make 27% from the general population, have a high clusterization index (74%), level of their multi drag resistance in 3 times exceeds that at «not Beijing» strains for which the share of clustering strains makes 11%.
topic mycobacterium tuberculosis
genetic typing
genetic profile
drag resistance
url https://bulletin.tomsk.ru/jour/article/view/1308
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