Absence of diurnal variation in visceromotor response to colorectal distention in normal Long Evans rats [version 1; referees: 2 approved]
Background: Enhanced colorectal sensitivity (i.e. visceral hypersensitivity) is thought to be a pathophysiological mechanism in irritable bowel syndrome (IBS). In healthy men a circadian variation in rectal perception to colonic distention was described. Disturbed day and night rhythms, which occur...
Main Authors: | Sara Botschuijver, Zhumei Yu, Olaf Welting, Cathy Cailotto, Andries Kalsbeek, Rene van den Wijngaard |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2016-01-01
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Series: | F1000Research |
Subjects: | |
Online Access: | http://f1000research.com/articles/5-98/v1 |
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