The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila

The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila

Antimicrobial peptides (AMPs) are small cationic molecules best known as mediators of the innate defence against microbial infection. While in vitro and ex vivo evidence suggest AMPs’ capacity to kill cancer cells, in vivo demonstration of an anti-tumour role of endogenous AMPs is lacking. Using a D...

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Bibliographic Details
Main Authors: Jean-Philippe Parvy, Yachuan Yu, Anna Dostalova, Shu Kondo, Alina Kurjan, Philippe Bulet, Bruno Lemaître, Marcos Vidal, Julia B Cordero
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-07-01
Series:eLife
Subjects:
defensin
antimicrobial peptides
Drosophila
tumours
TNF
Phosphatidylserine
Online Access:https://elifesciences.org/articles/45061

Internet

https://elifesciences.org/articles/45061

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