Cancer neoantigen prioritization through sensitive and reliable proteogenomics analysis

Identifying mutation-derived neoantigens by proteogenomics requires robust strategies for quality control. Here, the authors propose peptide retention time as an evaluation metric for proteogenomics quality control methods, and develop a deep learning algorithm for accurate retention time prediction...

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Bibliographic Details
Main Authors: Bo Wen, Kai Li, Yun Zhang, Bing Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15456-w