5′-hydroxy Auraptene stimulates osteoblast differentiation of bone marrow-derived mesenchymal stem cells via a BMP-dependent mechanism

5′-hydroxy Auraptene stimulates osteoblast differentiation of bone marrow-derived mesenchymal stem cells via a BMP-dependent mechanism

Abstract Background Identifying bone anabolic agents is a superior strategy for the treatment of osteoporosis. Naturally, derived coumarin derivatives have shown osteoanabolic effect in vitro and in vivo. In this study, we investigated the effect of 5′-Hydroxy Auraptene (5′-HA), a coumarin derivativ...

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Bibliographic Details
Main Authors: Basem M. Abdallah, Enas M. Ali
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Biomedical Science
Subjects:
Mesenchymal stem cells
BMSCs
Osteoblast
Adipocyte
5-hydroxy aurapten
Osteoblast differentiation
Online Access:http://link.springer.com/article/10.1186/s12929-019-0544-7

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http://link.springer.com/article/10.1186/s12929-019-0544-7

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