Analytical investigation of magnetic field effects on Proton lateral deflection and penetrating depth in the water phantom: A relativistic approach

Background: Integrated proton therapy - MRI systems are capable of delivering high doses to the target tissues near sensitive organs and achieve better therapeutic results; however, the applied magnetic field for imaging, influences the protons path, changes the penetration depth and deflects the...

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Main Authors: Mohammad Javad Tahmasebi Birgani, Nahid Chegeni, Mansour Zabihzadeh, Marziyeh Tahmasbi
Format: Article
Language:English
Published: Electronic Physician 2017-12-01
Series:Electronic Physician
Subjects:
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843418/
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spelling doaj-e17d74d49b054c4597b4505c1262cf1b2020-11-25T02:28:20ZengElectronic PhysicianElectronic Physician2008-58422008-58422017-12-019125932593910.19082/5932Analytical investigation of magnetic field effects on Proton lateral deflection and penetrating depth in the water phantom: A relativistic approachMohammad Javad Tahmasebi BirganiNahid ChegeniMansour ZabihzadehMarziyeh TahmasbiBackground: Integrated proton therapy - MRI systems are capable of delivering high doses to the target tissues near sensitive organs and achieve better therapeutic results; however, the applied magnetic field for imaging, influences the protons path, changes the penetration depth and deflects the particles, laterally, leading to dose distribution variations. Objective: To determine the effects of a magnetic field on the range and the lateral deflection of protons, analytically. Methods: An analytical survey based on protons energy and range power law relation, without using small angle assumption was done. The penetration depth and lateral deflection of protons with therapeutic energy ranges 60- 250 MeV in the presence of uniform magnetic fields of 0-10T intensities, were calculated analytically. Calculations were done for relativistic conditions with Mathematica software version 7.0, and MATLAB 7.0 was applied to plot curves and curve fittings. Results: In the presence of a magnetic field, the depth of Bragg peak was decreased and it was shifted laterally. A second order polynomial model with power equation for its coefficients and a power model with quadratic polynomial coefficients predicted the maximum lateral deflection (ymax) and maximum penetration depth (zmax) variations with energy and magnetic field intensity, respectively. Conclusion: The applied correction for deflection angle will give more reliable results in initial energy of 250 MeV and 3T magnetic field intensity. For lower energies and magnetic field intensities the differences are negligible, clinicallyhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843418/Proton radiation therapyPenetration depthLateral deflection
collection DOAJ
language English
format Article
sources DOAJ
author Mohammad Javad Tahmasebi Birgani
Nahid Chegeni
Mansour Zabihzadeh
Marziyeh Tahmasbi
spellingShingle Mohammad Javad Tahmasebi Birgani
Nahid Chegeni
Mansour Zabihzadeh
Marziyeh Tahmasbi
Analytical investigation of magnetic field effects on Proton lateral deflection and penetrating depth in the water phantom: A relativistic approach
Electronic Physician
Proton radiation therapy
Penetration depth
Lateral deflection
author_facet Mohammad Javad Tahmasebi Birgani
Nahid Chegeni
Mansour Zabihzadeh
Marziyeh Tahmasbi
author_sort Mohammad Javad Tahmasebi Birgani
title Analytical investigation of magnetic field effects on Proton lateral deflection and penetrating depth in the water phantom: A relativistic approach
title_short Analytical investigation of magnetic field effects on Proton lateral deflection and penetrating depth in the water phantom: A relativistic approach
title_full Analytical investigation of magnetic field effects on Proton lateral deflection and penetrating depth in the water phantom: A relativistic approach
title_fullStr Analytical investigation of magnetic field effects on Proton lateral deflection and penetrating depth in the water phantom: A relativistic approach
title_full_unstemmed Analytical investigation of magnetic field effects on Proton lateral deflection and penetrating depth in the water phantom: A relativistic approach
title_sort analytical investigation of magnetic field effects on proton lateral deflection and penetrating depth in the water phantom: a relativistic approach
publisher Electronic Physician
series Electronic Physician
issn 2008-5842
2008-5842
publishDate 2017-12-01
description Background: Integrated proton therapy - MRI systems are capable of delivering high doses to the target tissues near sensitive organs and achieve better therapeutic results; however, the applied magnetic field for imaging, influences the protons path, changes the penetration depth and deflects the particles, laterally, leading to dose distribution variations. Objective: To determine the effects of a magnetic field on the range and the lateral deflection of protons, analytically. Methods: An analytical survey based on protons energy and range power law relation, without using small angle assumption was done. The penetration depth and lateral deflection of protons with therapeutic energy ranges 60- 250 MeV in the presence of uniform magnetic fields of 0-10T intensities, were calculated analytically. Calculations were done for relativistic conditions with Mathematica software version 7.0, and MATLAB 7.0 was applied to plot curves and curve fittings. Results: In the presence of a magnetic field, the depth of Bragg peak was decreased and it was shifted laterally. A second order polynomial model with power equation for its coefficients and a power model with quadratic polynomial coefficients predicted the maximum lateral deflection (ymax) and maximum penetration depth (zmax) variations with energy and magnetic field intensity, respectively. Conclusion: The applied correction for deflection angle will give more reliable results in initial energy of 250 MeV and 3T magnetic field intensity. For lower energies and magnetic field intensities the differences are negligible, clinically
topic Proton radiation therapy
Penetration depth
Lateral deflection
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843418/
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