Pharmacokinetics in routine haemophilia clinical practice: rationale and modalities—a practical review
Prophylactic therapy with exogenous clotting factor concentrates in haemophilia A and B aims to achieve levels of circulating FVIII or FIX that are adequate for the prevention or reduction of spontaneous joint bleeding. Historically, a minimum trough level of at least 1% of the normal levels of circ...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2020-10-01
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| Series: | Therapeutic Advances in Hematology |
| Online Access: | https://doi.org/10.1177/2040620720966888 |