T-Regulatory Cells Confer Increased Myelination and Stem Cell Activity after Stroke-Induced White Matter Injury

Stroke-induced hypoxia causes oligodendrocyte death due to inflammation, lack of oxygen and exacerbation of cell death. Bone marrow-derived stem cells (BMSCs) possess an endogenous population of T-regulatory cells (T<sub>regs</sub>) which reduce secretion of pro-inflammatory cytokines th...

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Bibliographic Details
Main Authors: Sydney Zarriello, Elliot G. Neal, Yuji Kaneko, Cesario V. Borlongan
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/8/4/537