Simultaneous Determination of Eight Alkaloids in Rat Plasma by UHPLC-MS/MS after Oral Administration of Coptis deltoidea C. Y. Cheng et Hsiao and Coptis chinensis Franch

Simultaneous Determination of Eight Alkaloids in Rat Plasma by UHPLC-MS/MS after Oral Administration of Coptis deltoidea C. Y. Cheng et Hsiao and Coptis chinensis Franch

A ultra-high performance liquid chromatography-electrospray ionization tandem mass spectrometry (UHPLC-ESI-MS/MS) method was successfully developed and validated for the identification and determination of eight alkaloids: tetrahydropalmatine (A); palmatine (B); magnoflorine (C); columbamine (D); be...

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Bibliographic Details
Main Authors: Lu Liu, Zhi-Bin Wang, Yang Song, Jing Yang, Li-Jun Wu, Bing-You Yang, Qiu-Hong Wang, Li-Qian Wang, Ru-Xuan Wang, Chun-Juan Yang
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Molecules
Subjects:
alkaloids
UHPLC-MS/MS
method development
rat plasma
Online Access:http://www.mdpi.com/1420-3049/21/7/913

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http://www.mdpi.com/1420-3049/21/7/913

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