Cytochrome P450 aromatase (CYP19) gene expression in ovarian granulose cells of hypothyroid rats induced by propylthiouracil

Thyroid hormones are proven to have a direct effect on granulose cells, luteal cells and oocytes due to their role in gonadotropin action on steroid hormone production. In vitro study showed that tiroxine (T4) on granulose cells can stimulate ovarian steroidogenesis. Moreover, high concentration of...

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Bibliographic Details
Main Author: Prihatin Broto Sukandar Sri Kadarsih Soejono Totok Utoro
Format: Article
Language:English
Published: Universitas Gadjah Mada 2014-08-01
Series:Journal of the Medical Sciences
Online Access:https://jurnal.ugm.ac.id/bik/article/view/5023