In vitro inhibition of proliferation, migration and epithelial-mesenchymal transition of human lens epithelial cells by fasudil

In vitro inhibition of proliferation, migration and epithelial-mesenchymal transition of human lens epithelial cells by fasudil

AIM: To study the potential role of fasudil as a treatment for posterior capsular opacification (PCO) of the human crystalline lens. METHODS: Human lens epithelial cells (HLECs; line SRA01/04) was exposed to transforming growth factor-β2 (TGF-β2) to induce the process of epithelial-mesenchymal tran...

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Bibliographic Details
Main Authors: Jing-Zhi Shao, Ying Qi, Shan-Shan Du, Wen-Wen Du, Fu-Zhen Li, Feng-Yan Zhang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2018-08-01
Series:International Journal of Ophthalmology
Subjects:
1257
fasudil
human lens epithelial cells
TGF-β2
Rho/Rock
epithelial-mesenchymal transition
Online Access:http://www.ijo.cn/en_publish/2018/8/20180802.pdf

Internet

http://www.ijo.cn/en_publish/2018/8/20180802.pdf

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