Acromegaly and papillary thyroid carcinoma: A case series
Acromegaly is a rare chronic disease and associated with an increased risk of malignancy. The issue of the risk of thyroid cancer in these patients is a topic of debate, and the number of large case–control studies is very limited. Several studies indicated that a chronic excess insulin-like growth...
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Wolters Kluwer Medknow Publications
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doaj-e16b5538d81b4f5da0523bd6a9155cbf2020-11-25T01:06:44ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362019-01-01241818110.4103/jrms.JRMS_969_18Acromegaly and papillary thyroid carcinoma: A case seriesMaryam HeidarpourHassan RezvanianAli KachueiAcromegaly is a rare chronic disease and associated with an increased risk of malignancy. The issue of the risk of thyroid cancer in these patients is a topic of debate, and the number of large case–control studies is very limited. Several studies indicated that a chronic excess insulin-like growth factor-1 stimulates the proliferation of various cell types and induces an antiapoptotic effect in thyroid follicular cells. In the literature, the risk of thyroid cancer was reported greater than five-fold. In this review, we will briefly summarize the studies available regarding thyroid cancer in patients with acromegaly and present three case reports.http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2019;volume=24;issue=1;spage=81;epage=81;aulast=Heidarpouracromegalymalignancythyroid cancer |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Maryam Heidarpour Hassan Rezvanian Ali Kachuei |
spellingShingle |
Maryam Heidarpour Hassan Rezvanian Ali Kachuei Acromegaly and papillary thyroid carcinoma: A case series Journal of Research in Medical Sciences acromegaly malignancy thyroid cancer |
author_facet |
Maryam Heidarpour Hassan Rezvanian Ali Kachuei |
author_sort |
Maryam Heidarpour |
title |
Acromegaly and papillary thyroid carcinoma: A case series |
title_short |
Acromegaly and papillary thyroid carcinoma: A case series |
title_full |
Acromegaly and papillary thyroid carcinoma: A case series |
title_fullStr |
Acromegaly and papillary thyroid carcinoma: A case series |
title_full_unstemmed |
Acromegaly and papillary thyroid carcinoma: A case series |
title_sort |
acromegaly and papillary thyroid carcinoma: a case series |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Research in Medical Sciences |
issn |
1735-1995 1735-7136 |
publishDate |
2019-01-01 |
description |
Acromegaly is a rare chronic disease and associated with an increased risk of malignancy. The issue of the risk of thyroid cancer in these patients is a topic of debate, and the number of large case–control studies is very limited. Several studies indicated that a chronic excess insulin-like growth factor-1 stimulates the proliferation of various cell types and induces an antiapoptotic effect in thyroid follicular cells. In the literature, the risk of thyroid cancer was reported greater than five-fold. In this review, we will briefly summarize the studies available regarding thyroid cancer in patients with acromegaly and present three case reports. |
topic |
acromegaly malignancy thyroid cancer |
url |
http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2019;volume=24;issue=1;spage=81;epage=81;aulast=Heidarpour |
work_keys_str_mv |
AT maryamheidarpour acromegalyandpapillarythyroidcarcinomaacaseseries AT hassanrezvanian acromegalyandpapillarythyroidcarcinomaacaseseries AT alikachuei acromegalyandpapillarythyroidcarcinomaacaseseries |
_version_ |
1725188537291112448 |