Acromegaly and papillary thyroid carcinoma: A case series

Acromegaly is a rare chronic disease and associated with an increased risk of malignancy. The issue of the risk of thyroid cancer in these patients is a topic of debate, and the number of large case–control studies is very limited. Several studies indicated that a chronic excess insulin-like growth...

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Main Authors: Maryam Heidarpour, Hassan Rezvanian, Ali Kachuei
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Journal of Research in Medical Sciences
Subjects:
Online Access:http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2019;volume=24;issue=1;spage=81;epage=81;aulast=Heidarpour
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spelling doaj-e16b5538d81b4f5da0523bd6a9155cbf2020-11-25T01:06:44ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362019-01-01241818110.4103/jrms.JRMS_969_18Acromegaly and papillary thyroid carcinoma: A case seriesMaryam HeidarpourHassan RezvanianAli KachueiAcromegaly is a rare chronic disease and associated with an increased risk of malignancy. The issue of the risk of thyroid cancer in these patients is a topic of debate, and the number of large case–control studies is very limited. Several studies indicated that a chronic excess insulin-like growth factor-1 stimulates the proliferation of various cell types and induces an antiapoptotic effect in thyroid follicular cells. In the literature, the risk of thyroid cancer was reported greater than five-fold. In this review, we will briefly summarize the studies available regarding thyroid cancer in patients with acromegaly and present three case reports.http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2019;volume=24;issue=1;spage=81;epage=81;aulast=Heidarpouracromegalymalignancythyroid cancer
collection DOAJ
language English
format Article
sources DOAJ
author Maryam Heidarpour
Hassan Rezvanian
Ali Kachuei
spellingShingle Maryam Heidarpour
Hassan Rezvanian
Ali Kachuei
Acromegaly and papillary thyroid carcinoma: A case series
Journal of Research in Medical Sciences
acromegaly
malignancy
thyroid cancer
author_facet Maryam Heidarpour
Hassan Rezvanian
Ali Kachuei
author_sort Maryam Heidarpour
title Acromegaly and papillary thyroid carcinoma: A case series
title_short Acromegaly and papillary thyroid carcinoma: A case series
title_full Acromegaly and papillary thyroid carcinoma: A case series
title_fullStr Acromegaly and papillary thyroid carcinoma: A case series
title_full_unstemmed Acromegaly and papillary thyroid carcinoma: A case series
title_sort acromegaly and papillary thyroid carcinoma: a case series
publisher Wolters Kluwer Medknow Publications
series Journal of Research in Medical Sciences
issn 1735-1995
1735-7136
publishDate 2019-01-01
description Acromegaly is a rare chronic disease and associated with an increased risk of malignancy. The issue of the risk of thyroid cancer in these patients is a topic of debate, and the number of large case–control studies is very limited. Several studies indicated that a chronic excess insulin-like growth factor-1 stimulates the proliferation of various cell types and induces an antiapoptotic effect in thyroid follicular cells. In the literature, the risk of thyroid cancer was reported greater than five-fold. In this review, we will briefly summarize the studies available regarding thyroid cancer in patients with acromegaly and present three case reports.
topic acromegaly
malignancy
thyroid cancer
url http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2019;volume=24;issue=1;spage=81;epage=81;aulast=Heidarpour
work_keys_str_mv AT maryamheidarpour acromegalyandpapillarythyroidcarcinomaacaseseries
AT hassanrezvanian acromegalyandpapillarythyroidcarcinomaacaseseries
AT alikachuei acromegalyandpapillarythyroidcarcinomaacaseseries
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