A Patient with Refractory Psoriasis Who Developed Sebaceous Carcinoma on the Neck during Cyclosporine Therapy and Showed Rapid Progression

A Patient with Refractory Psoriasis Who Developed Sebaceous Carcinoma on the Neck during Cyclosporine Therapy and Showed Rapid Progression

We report a patient who developed sebaceous carcinoma on the neck during therapy with immunosuppressive agents (cyclosporine, corticosteroid, methotrexate) for refractory psoriasis vulgaris, which showed rapid enlargement, leading to a fatal outcome. Multiple-organ metastases were detected. Weekly c...

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Bibliographic Details
Main Authors: Tomoko Shima, Yuki Yamamoto, Hisako Okuhira, Naoya Mikita, Fukumi Furukawa
Format: Article
Language:English
Published: Karger Publishers 2016-06-01
Series:Case Reports in Dermatology
Subjects:
Cyclosporine
Sebaceous carcinoma
Carboplatin + paclitaxel therapy
Psoriasis vulgaris
Online Access:http://www.karger.com/Article/FullText/446342
Description
Summary:We report a patient who developed sebaceous carcinoma on the neck during therapy with immunosuppressive agents (cyclosporine, corticosteroid, methotrexate) for refractory psoriasis vulgaris, which showed rapid enlargement, leading to a fatal outcome. Multiple-organ metastases were detected. Weekly carboplatin + paclitaxel therapy resulted in the disappearance of tumor cells, but the patient died of febrile neutropenia. The development of sebaceous carcinoma is rare among psoriasis patients receiving immunosuppressive agents including cyclosporine.
ISSN:1662-6567

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