Exendin-4 Improves Diabetic Kidney Disease in C57BL/6 Mice Independent of Brown Adipose Tissue Activation
Background. The role of exendin-4 in brown adipose tissue (BAT) activation was not very clear. This study is to verify the role of BAT involved in renal benefits of exendin-4 in diabetes mellitus (DM). Methods. In vivo, C57BL/6 mice were randomly divided into nondiabetic (control) and diabetic group...
Main Authors: | Shu Fang, Yingying Cai, Fuping Lyu, Hongbin Zhang, Chunyan Wu, Yanmei Zeng, Cunxia Fan, Shaozhou Zou, Yudan Zhang, Ping Li, Ling Wang, YaomingXue, Meiping Guan |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2020-01-01
|
Series: | Journal of Diabetes Research |
Online Access: | http://dx.doi.org/10.1155/2020/9084567 |
Similar Items
-
Transplantation of brown adipose tissue up-regulates miR-99a to ameliorate liver metabolic disorders in diabetic mice by targeting NOX4
by: Ping Li, et al.
Published: (2020-01-01) -
Effect of High-Fat Diet on Peripheral Neuropathy in C57BL/6 Mice
by: Lingling Xu, et al.
Published: (2014-01-01) -
Effects of exendin-4 on the intrarenal renin-angiotensin system and interstitial fibrosis in unilateral ureteral obstruction mice: Exendin-4 and unilateral ureteral obstruction
by: Ying Le, et al.
Published: (2016-11-01) -
Effects of metformin on metabolism of white and brown adipose tissue in obese C57BL/6J mice
by: Tao Yuan, et al.
Published: (2019-11-01) -
Increased oxidative stress, inflammation and fibrosis in perirenal adipose tissue of patients with cortisol-producing adenoma
by: Chunyan Wu, et al.
Published: (2019-01-01)