Modulation of anti-tumor immunity by the brain’s reward system
Neural activation can have wide ranging effects beyond central and peripheral nervous system. This work shows that chemogenetic activation of the brain’s reward system ventral tegmental area (VTA) can boost mice’s immune function, confer anti-tumor immunity, and reduce tumor mass in experimental rod...
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Bibliographic Details
| Main Authors: |
Tamar L Ben-Shaanan,
Maya Schiller,
Hilla Azulay-Debby,
Ben Korin,
Nadia Boshnak,
Tamar Koren,
Maria Krot,
Jivan Shakya,
Michal A. Rahat,
Fahed Hakim,
Asya Rolls |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2018-07-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-05283-5
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