Chemical Constituents from Scindapsus officinalis (Roxb.) Schott. and Their Anti–Inflammatory Activities

Chemical Constituents from Scindapsus officinalis (Roxb.) Schott. and Their Anti–Inflammatory Activities

One new monoterpene glycoside (1), one new phenyl glycoside (2), one new caffeoyl derivative (3), were isolated from Scindapsus officinalis (Roxb.) Schott., along with four known compounds (4–7). Structures of the isolated compounds were elucidated by extensive analysis of spectroscopic da...

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Bibliographic Details
Main Authors: Hongjing Dong, Yanling Geng, Xueyong Wang, Xiangyun Song, Xiao Wang, Jinqian Yu
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
Scindapsus officinalis
monoterpene glycoside
phenyl glycoside
caffeoyl derivative
anti-inflammatory activity
Online Access:http://www.mdpi.com/1420-3049/23/10/2577
Description
Summary:One new monoterpene glycoside (1), one new phenyl glycoside (2), one new caffeoyl derivative (3), were isolated from Scindapsus officinalis (Roxb.) Schott., along with four known compounds (4–7). Structures of the isolated compounds were elucidated by extensive analysis of spectroscopic data, especially 2D NMR data and comparison with literatures. All isolates were evaluated for anti-inflammatory activity against nitric oxide (NO) production in vitro. Compounds 3 and 7 exhibited moderate inhibitory effects on NO production with IC50 values of 12.2 ± 0.8 and 18.9 ± 0.3 μM, respectively.
ISSN:1420-3049

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