Hypermethylation in the promoter of the MTHFR gene is associated with diabetic complications and biochemical indicators

Hypermethylation in the promoter of the MTHFR gene is associated with diabetic complications and biochemical indicators

Abstract Background DNA methylation is an epigenetic mechanism for regulating the transcription of many genes and has been linked to the development of various diseases. A promising gene to investigate is methylenetetrahydrofolate reductase (MTHFR), since the enzyme methylenetetrahydrofolate reducta...

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Bibliographic Details
Main Authors: Mayara Karla dos Santos Nunes, Alexandre Sérgio Silva, Isabella Wanderley de Queiroga Evangelista, João Modesto Filho, Cecília Neta Alves Pegado Gomes, Rayner Anderson Ferreira do Nascimento, Rafaella Cristhine Pordeus Luna, Maria José de Carvalho Costa, Naila Francis Paulo de Oliveira, Darlene Camati Persuhn
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Diabetology & Metabolic Syndrome
Online Access:http://link.springer.com/article/10.1186/s13098-017-0284-3

Internet

http://link.springer.com/article/10.1186/s13098-017-0284-3

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