On the interactions between mesenchymal stem cells and regulatory T cells for immunomodulation in transplantation

On the interactions between mesenchymal stem cells and regulatory T cells for immunomodulation in transplantation

Experimental studies have established the use of mesenchymal stem cells (MSC) as a candidate immunosuppressive therapy. MSC exert their immunomodulatory function through the inhibition of CD4+ and CD8+ T-cell proliferation. It is unknown whether MSC impair the immunosuppressive function of regulator...

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Bibliographic Details
Main Authors: Anja U. Engela, Carla C. Baan, Frank J.M.F. Dor, Willem eWeimar, Martin J. Hoogduijn
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Immunology
Subjects:
Transplantation
Regulatory T Cell
mesenchymal stem cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00126/full

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