Rate differences between first and second primary cancers may outline immune dysfunction as a key risk factor

Rate differences between first and second primary cancers may outline immune dysfunction as a key risk factor

Abstract Background Many cancers are increased in immunosuppressed patients and evidence is accumulating that immune dysfunction may be a contributing risk factor for second primary cancers (SPCs). The aim of this study was to explore the potential influence of immune mechanisms in SPC. Methods We u...

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Bibliographic Details
Main Authors: Guoqiao Zheng, Kristina Sundquist, Jan Sundquist, Asta Försti, Akseli Hemminki, Kari Hemminki
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:Cancer Medicine
Subjects:
cancer risk
immune suppression
multiple cancers
risk factors
Online Access:https://doi.org/10.1002/cam4.3454

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