Berberine increases glucose uptake and intracellular ROS levels by promoting Sirtuin 3 ubiquitination

Berberine increases glucose uptake and intracellular ROS levels by promoting Sirtuin 3 ubiquitination

Objective: Berberine improves insulin sensitivity and ovulation function in PCOS patients. However, the mechanism by which berberine initiates glucose metabolism-related signaling pathways in ovarian cells remains unknown. This study unveiled a new mechanism by which berberine promotes ovarian cell...

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Bibliographic Details
Main Authors: Wei Li, Dan Li, Hongying Kuang, Xiaoling Feng, Wenxia Ai, Ying Wang, Simao Shi, Jing Chen, Ruifeng Fan
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Berberine
Glucose
Mitochondrial function
ROS
SIRT3
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219351868

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