Machine Learning Uses Chemo-Transcriptomic Profiles to Stratify Antimalarial Compounds With Similar Mode of Action
The rapid development of antimalarial resistance motivates the continued search for novel compounds with a mode of action (MoA) different to current antimalarials. Phenotypic screening has delivered thousands of promising hit compounds without prior knowledge of the compounds’ exact target or MoA. W...
Main Authors: | Ashleigh van Heerden, Roelof van Wyk, Lyn-Marie Birkholtz |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-06-01
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Series: | Frontiers in Cellular and Infection Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2021.688256/full |
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