FBXW7 expression is associated with prognosis and chemotherapeutic outcome in Chinese patients with gastric adenocarcinoma

FBXW7 expression is associated with prognosis and chemotherapeutic outcome in Chinese patients with gastric adenocarcinoma

Abstract Background FBXW7, a component of the Skp-Cullin1-F-box, mediates target protein recognition. It is a tumor suppressor gene that plays a role in the regulation of cell cycle exit and reentry via c-Myc, c-Jun and Notch degradation. There are few studies, particularly involving a large patient...

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Bibliographic Details
Main Authors: Mao-Ran Li, Chun-Chao Zhu, Tian-Long Ling, Ye-Qian Zhang, Jia Xu, En-Hao Zhao, Gang Zhao
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Gastroenterology
Subjects:
FBXW7
Gastric cancer
Prognosis
Chemotherapeutic outcome
Online Access:http://link.springer.com/article/10.1186/s12876-017-0616-7

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http://link.springer.com/article/10.1186/s12876-017-0616-7

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