Application of Multilayer Evidence for Annotation of C-Terminal <i>BRCA2</i> Variants
The clinical relevance of the <i>BRCA2</i> C-terminal stop codon variants is controversial. The pathogenic role of the germline <i>BRCA2</i> c.9976A>T and c.10095delinsGAATTATATCT variants in hereditary breast and ovarian cancer (HBOC) patients was evaluated. An associatio...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-02-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/13/4/881 |