Limitations of alignment-free tools in total RNA-seq quantification
Abstract Background Alignment-free RNA quantification tools have significantly increased the speed of RNA-seq analysis. However, it is unclear whether these state-of-the-art RNA-seq analysis pipelines can quantify small RNAs as accurately as they do with long RNAs in the context of total RNA quantif...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12864-018-4869-5 |