Association of Limb-Girdle muscular dystrophy with multiple sclerosis: A case report

• Main Authors: Mahsa Arzani, Hamed Rezaei, Abdorreza Naser Moghadasi
• Format: Article
• Language: English
• Published: Babol University of Medical Sciences 2018-01-01
• Series: Caspian Journal of Internal Medicine
• Subjects: Limb-Girdle Muscular Dystrophy; Multiple Sclerosis; Myopathy
• Online Access: http://caspjim.com/browse.php?a_code=A-10-646-1&slc_lang=en&sid=1

Background: The association of limb-girdle muscular dystrophy (LGMD) with other neurological disorders is uncommon. Case presentation: We report a 25-year-old female with LGMD who suffered from slowly progressive proximal muscular weakness and atrophy since she was 12 years of age. The patient recently presented with acute loss of left side visual acuity. After evaluation, findings were suggestive of multiple sclerosis. Conclusions: This is the first report of LGMD in association with MS. The simultaneous occurrence of MS with myopathies may be incidental but there may be a genetic susceptibility for both diseases. This comorbidity may influence the treatment of MS