Structure-Dependent Effects of Bisphosphonates on Inflammatory Responses in Cultured Neonatal Mouse Calvaria

Structure-Dependent Effects of Bisphosphonates on Inflammatory Responses in Cultured Neonatal Mouse Calvaria

Bisphosphonates (BPs) are classified into two groups, according to their side chain structures, as nitrogen-containing BPs (NBPs) and non-nitrogen-containing BPs (non-NBPs). In this study, we examined the effects of NBPs and non-NBPs on inflammatory responses, by quantifying the inflammatory mediato...

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Bibliographic Details
Main Authors: Keiko Suzuki, Sadaaki Takeyama, Shinobu Murakami, Masahiro Nagaoka, Mirei Chiba, Kaoru Igarashi, Hisashi Shinoda
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Antioxidants
Subjects:
bisphosphonate
antioxidant
anti-inflammatory
PGE<sub>2</sub>
NO
peroxynitrite
Online Access:https://www.mdpi.com/2076-3921/9/6/503

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