Analgesic Effects of Bee Venom Derived Phospholipase A2 in a Mouse Model of Oxaliplatin-Induced Neuropathic Pain

Analgesic Effects of Bee Venom Derived Phospholipase A2 in a Mouse Model of Oxaliplatin-Induced Neuropathic Pain

A single infusion of oxaliplatin, which is widely used to treat metastatic colorectal cancer, induces specific sensory neurotoxicity signs that are triggered or aggravated when exposed to cold or mechanical stimuli. Bee Venom (BV) has been traditionally used in Korea to treat various pain symptoms....

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Bibliographic Details
Main Authors: Dongxing Li, Younju Lee, Woojin Kim, Kyungjin Lee, Hyunsu Bae, Sun Kwang Kim
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Toxins
Subjects:
phospholipase A2
Bee Venom
oxaliplatin
neuropathic pain
noradrenergic
Online Access:http://www.mdpi.com/2072-6651/7/7/2422

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