Glutathione and Mitochondria

Glutathione (GSH) is the main nonprotein thiol in cells whose functions are dependent on the redox-active thiol of its cysteine moiety that serves as a cofactor for a number of antioxidant and detoxifying enzymes. While synthesized exclusively in the cytosol from its constituent amino acids, GSH is...

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Bibliographic Details
Main Authors: Vicent eRibas, Carmen eGarcia-Ruiz, Jose C eFernandez-Checa
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00151/full