Calunduloside E inhibits HepG2 cell proliferation and migration via p38/JNK-HMGB1 signalling axis

Calunduloside E inhibits HepG2 cell proliferation and migration via p38/JNK-HMGB1 signalling axis

High-mobility group box 1 (HMGB1), a highly conserved chromosome protein, is considered as a potential therapeutic target and novel biomarker because of its regulation in the proliferation and metastasis of Hepatocellular carcinoma (HCC). Calenduloside E (CE), a natural active product, has been repo...

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Bibliographic Details
Main Authors: Shengnan Wang, Xuelei Chen, Jin Cheng, Tianyu Cai, Xiaoming Wu, Zhenyu Cheng, Shimei Qi, Zhilin Qi
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Journal of Pharmacological Sciences
Subjects:
Calunduloside E
HepG2 cells
HMGB1
Proliferation
Migration
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000475

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