An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery

SUMMARY Anti-cancer drug development involves enormous expenditure and risk. For rapid and economical identification of novel, bioavailable anti-tumour chemicals, the use of appropriate in vivo tumour models suitable for large-scale screening is key. Using a Drosophila Ras-driven tumour model, we de...

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Bibliographic Details
Main Authors: Lee F. Willoughby, Tanja Schlosser, Samuel A. Manning, John P. Parisot, Ian P. Street, Helena E. Richardson, Patrick O. Humbert, Anthony M. Brumby
Format: Article
Language:English
Published: The Company of Biologists 2013-03-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/6/2/521