Dysregulation of Complement Activation and Placental Dysfunction: A Potential Target to Treat Preeclampsia?

Dysregulation of Complement Activation and Placental Dysfunction: A Potential Target to Treat Preeclampsia?

Preeclampsia is one of the leading causes of maternal and neonatal mortality and morbidity worldwide, affecting 2–8% of all pregnancies. Studies suggest a link between complement activation and preeclampsia. The complement system plays an essential role in the innate immunity, leading to opsonizatio...

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Bibliographic Details
Main Authors: E. Pierik, Jelmer R. Prins, Harry van Goor, Gustaaf A. Dekker, Mohamed R. Daha, Marc A. J. Seelen, Sicco A. Scherjon
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
complement
placental dysfunction
preeclampsia
pregnancy
treatment
review
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03098/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.03098/full

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